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- Null method to estimate the maximal PA at subsaturating concentrations of agonistGermann, A. L., Pierce, S. R., Steinbach, J. H. & Akk, G., Jan 6 2025, In: Journal of General […]
- Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent NeurosteroidsAkkerman, V., Reinholdt, P., Schnoor-Madsen, R., Lauritsen, L., Bader, J., Qian, M., Xu, Y., Akk, G., Scheidt, H. A., Müller, P., […]
- AI is a viable alternative to high throughput screening: a 318-target studyWallach, I., Bernard, D., Nguyen, K., Ho, G., Morrison, A., Stecula, A., Rosnik, A., O’Sullivan, A. M., Davtyan, A., […]
- Correction to: AI is a viable alternative to high throughput screening: a 318-target study (Scientific Reports, (2024), 14, 1, (7526), 10.1038/s41598-024-54655-z)The Atomwise AIMS Program, Dec 2024, In: Scientific reports. 14, […]
- Direct measurements of neurosteroid binding to specific sites on GABAA receptorsChintala, S. M., Tateiwa, H., Qian, M., Xu, Y., Amtashar, F., Chen, Z. W., Kirkpatrick, C. C., Bracamontes, J., Germann, […]
- Inhibitory Actions of Potentiating Neuroactive Steroids in the Human a1b3g2L g-Aminobutyric Acid Type A ReceptorPierce, S. R., Germann, A. L., Covey, D. F., Evers, A. S., Steinbach, J. H. & […]
- Three classes of propofol binding sites on GABAA receptorsChen, Z. W., Chintala, S. M., Bracamontes, J., Sugasawa, Y., Pierce, S. R., Varga, B. R., Smith, E. H., Edge, C. J., […]
- Potentiation of the GABAAR reveals variable energetic contributions by etiocholanolone and propofolPierce, S. R., Xu, S. Q., Germann, A. L., Steinbach, J. H. & Akk, G., Jul 16 2024, In: […]
- Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABAA receptor and CaV2.2 channelTae, H. S., Ortells, M. O., […]
- Comparison of Behavioral Effects of GABAergic Low- and High-Efficacy Neuroactive Steroids in the Zebrafish Larvae AssayGermann, A. L., Xu, Y., Covey, D. F., Evers, A. S. & Akk, G., Mar […]
- UNC-49 is a redox-sensitive GABAA receptor that regulates the mitochondrial unfolded protein response cell nonautonomouslyPohl, F., Germann, A. L., Mao, J., Hou, S., Bakare, B., Lin, P. K. T., Yates, […]
- Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABAA ReceptorArias, H. R., Pierce, S. R., Germann, A. L., Xu, S. Q., Ortells, M. O., Sakamoto, S., Manetti, […]
- Mutational Analysis of Anesthetic Binding Sites and Their Effects on GABAA Receptor Activation and Modulation by Positive Allosteric Modulators of the α7 Nicotinic ReceptorPierce, S. R., Germann, A. L., Xu, […]
- The Mechanism of Enantioselective Neurosteroid Actions on GABAA ReceptorsTateiwa, H., Chintala, S. M., Chen, Z., Wang, L., Amtashar, F., Bracamontes, J., Germann, A. L., Pierce, S. R., Covey, D. F., […]
- Modulation of the mammalian GABAA receptor by type I and type II positive allosteric modulators of the α7 nicotinic acetylcholine receptorArias, H. R., Germann, A. L., Pierce, S. R., Sakamoto, […]
- Ms. Rabia Moin: A Linchpin in the Road to Success of Current NeuropharmacologyNicoletti, F. & Akk, G., Oct 2022, In: Current Neuropharmacology. 20, 10, p. 1806 1 p.Research output: Contribution […]
- Activation of the Rat α1β2ε GABAA Receptor by Orthosteric and Allosteric AgonistsGermann, A. L., Burbridge, A. B., Pierce, S. R. & Akk, G., Jul 2022, In: Biomolecules. 12, 7, 868.Research […]
- Neurosteroid Modulation of GABAA Receptor Function by Independent Action at Multiple Specific Binding SitesWang, L., Covey, D. F., Akk, G. & Evers, A., May 2022, In: Current Neuropharmacology. 20, 5, […]
- (+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loopArias, H. R., Borghese, C. M., Germann, A. L., Pierce, S. R., […]
- The Sulfated Steroids Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate Inhibit the a1b3c2L GABAA Receptor by Stabilizing a Novel Nonconducting StatePierce, S. R., Germann, A. L., Steinbach, J. H. & Akk, G., […]